Methyl 5-chloropyrazine-2-carboxylate → HCID 59191557, compound

Participants

Reaction Steps

According to the protocol described below for example 46, 4,5-dimethyl-3-((R)-3-methylpiperazin-1-yl)-6-pyridin-4-ylmethyl-pyridazine (155 mg, 0.51 mmol) and 5-chloro-pyrazine-2-carboxylic acid methyl ester (99 mg, 0.56 mmol) afforded the title compound as an orange oil (123 mg, 56%).

Provenance & Evidence