HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-2-methyl-1-propanol → 5-Chloro-4-(3-chlorophenyl)-pyridine-2-carboxylic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-2-methyl-1-propanol | HCID 11807 | — |
| Reactant | 5-Chloro-4-(3-chlorophenyl)-pyridine-2-carboxylic acid | HCID 90203766 | — |
| Product | 5-Chloro-4-(3-chlorophenyl)-pyridine-2-carboxylic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide | HCID 76281998 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 5-chloro-4-(3-chlorophenyl)-pyridine-2-carboxylic acid and 2-amino-2-methyl-1-propanol (CAN 124-68-5) as starting materials and isolated (13 mg, 38%) as colorless oil; MS (ESI, m/z): 339.0, 341.0 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409866B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-2b59f2162a254c9aaa3ebe6ebc239d7d |
| Source note | uspto-grants-2016_08 |