HuagongsheHuagongshe Chemistry Print Report · For research reference only
Leucinamide → 5-Chloro-4-(3-chloro-phenyl)-pyridine-2-carboxylic acid ((S)-1-carbamoyl-3-methyl-butyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Leucinamide | HCID 69640 | — |
| Reactant | 5-Chloro-4-(3-chlorophenyl)-pyridine-2-carboxylic acid | HCID 90203766 | — |
| Product | 5-Chloro-4-(3-chloro-phenyl)-pyridine-2-carboxylic acid ((S)-1-carbamoyl-3-methyl-butyl)-amide | HCID 76281997 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 5-chloro-4-(3-chlorophenyl)-pyridine-2-carboxylic acid and (2S)-2-amino-4-methyl-pentanamide (CAN 687-51-4) as starting materials and isolated (8 mg, 21%) as colorless oil; MS (ESI, m/z): 380.1, 382.1 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409866B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-a5923f24290c4cce9901509cc71cfc7c |
| Source note | uspto-grants-2016_08 |