HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzyl bromide → 2,5-Dichloro-4-(4-fluoro-benzyloxy)-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzyl bromide | HCID 68021 | — |
| Reactant | HCID 178516192 | HCID 178516192 | — |
| Product | 2,5-Dichloro-4-(4-fluoro-benzyloxy)-pyridine | HCID 90203266 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 12a, using 2,5-dichloro-4-pyridinol (CAN 847664-65-7) and 1-(bromomethyl)-4-fluoro-benzene (CAN 459-46-1) as starting materials and isolated (1.03 g, 62%) as white solid; LC-MS (UV peak area, m/z) 98.6%, 272.0040 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409866B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-38e42d523a234b33be1164532d9ce54d |
| Source note | uspto-grants-2016_08 |