Hydrochloric Acid → 2-Amino-2-ethyl-N-methyl-butyramide hydrochloride

HRID 1480094Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1480094
[CH3:1][NH:2][C:3]([C:5]([NH:10]C(=O)OC(C)(C)C)([CH2:8][CH3:9])[CH2:6][CH3:7])=[O:4].[ClH:18]>C(OCC)(=O)C>[ClH:18].[NH2:10][C:5]([CH2:8][CH3:9])([CH2:6][CH3:7])[C:3]([NH:2][CH3:1])=[O:4]

Komponenten

4

Edukt 2

HCID 313Hydrochloric AcidHCID 86674754tert-Butyl 3-(methylcarbamoyl)pentan-3-ylcarbamate

Produkt 1

HCID 895221382-Amino-2-ethyl-N-methyl-butyramide hydrochlorideAusbeute 75 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

A mixture of tert-butyl 3-(methylcarbamoyl)pentan-3-ylcarbamate (0.18 g, 0.74 mmol) in 10 ml saturated hydrochloride in ethyl acetate was stirred for 60 min at room temperature. Then the solution was evaporated to dryness to obtain the product (80 mg, 75%) as a light yellow solid. MS (ESI, m/z): 145.2 (M+H+)

Aufarbeitung

  1. customThen the solution was evaporated to dryness

Quellen und Nachweise

ORD-Eintrag
ord-8e33696703874798bf0ac045d1ca81ed
Quelldatensatz
uspto-grants-2016_08
Patentnummer
US09409866B2

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