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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1480116Generated: October 30, 2026

2-Propanol, 1-amino-2-methyl- → HCID 76283954, compound

https://huagongshe.com/reaction/1480116

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Propanol, 1-amino-2-methyl-HCID 95102—
Reactant5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acidHCID 90203674—
ProductHCID 76283954HCID 76283954—

Reaction Steps

The title compound was synthesized in analogy to Example 24d, using 5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (Example 48c) and 1-amino-2-methylpropan-2-ol (CAN 2854-16-2) as starting materials and isolated (28 mg, 34%) as a yellow oil; MS (ESI, m/z): 333.5 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09409866B2
Source datasetuspto-grants-2016_08
ORD IDord-769f7c408d224153b950096d808326e5
Source noteuspto-grants-2016_08