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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1480131Generated: October 31, 2026

Tert-Butylamine → HCID 90204122, compound

https://huagongshe.com/reaction/1480131

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-ButylamineHCID 6385—
Reactant5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acidHCID 90203674—
ProductHCID 90204122HCID 90204122—

Reaction Steps

The title compound was synthesized in analogy to Example 63b, using 5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (Example 48c) and 2-methylpropan-2-amine (CAN 75-64-9) as starting materials and isolated (12.5 mg, 17%) as colorless oil; MS (ESI, m/z): 317.1 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09409866B2
Source datasetuspto-grants-2016_08
ORD IDord-061e027c90cc4b649a7a13ed8c722fe0
Source noteuspto-grants-2016_08