HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Oxa-5-azaspiro[3.4]octane oxalate → HCID 90203652, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Oxa-5-azaspiro[3.4]octane oxalate | HCID 72207353 | — |
| Reactant | 5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid | HCID 90203674 | — |
| Product | HCID 90203652 | HCID 90203652 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 63b, using 5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (Example 48c) and 2-Oxa-5-aza-spiro[3.4]octane oxalate (CAN 1380571-82-3) as starting materials and isolated (37.6 mg, 46%) as colorless oil; MS (ESI, m/z): 357.1 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409866B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-ab3dcebde17246d79d0b90b70b962f8e |
| Source note | uspto-grants-2016_08 |