Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1480136Generated: October 30, 2026

5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid → HCID 76283952, compound

https://huagongshe.com/reaction/1480136

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acidHCID 90203674—
ReactantHCID 90203860HCID 90203860—
ProductHCID 76283952HCID 76283952—

Reaction Steps

The title compound was synthesized in analogy to Example 63b, using 5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (Example 48c) and 2-Methyl-2-methylamino-butyramide hydrochloride (CAN 18305-22-1) as starting materials and isolated (19.6 mg, 16%) as a white solid; MS (ESI, m/z): 360.5 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09409866B2
Source datasetuspto-grants-2016_08
ORD IDord-9f83da892f994a9c83b1cb853d56e0e3
Source noteuspto-grants-2016_08