Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Amino-3-methanesulfonyl-2-methyl-propionitrile → 5-Bromo-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (1-cyano-2-methanesulfonyl-1-methyl-ethyl)-amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Amino-3-methanesulfonyl-2-methyl-propionitrile | HCID 90203372 | — |
| 반응물 | 5-Bromo-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid | HCID 90204121 | — |
| 생성물 | 5-Bromo-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (1-cyano-2-methanesulfonyl-1-methyl-ethyl)-amide | HCID 90204599 | — |
반응 단계
The title compound was synthesized in analogy to Example 78e, using 5-Bromo-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (Example 78d) and 2-Amino-3-methanesulfonyl-2-methyl-propionitrile (Example 80a) as starting material and isolated (570 mg, 77%) as a yellow oil; MS (ESI, m/z): 444.3 (M+H+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09409866B2 |
| 출처 데이터셋 | uspto-grants-2016_08 |
| ORD ID | ord-0703143b882b4fad92b5253bf90c8be8 |
| 출처 메모 | uspto-grants-2016_08 |