HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-tert-Butylethylamine → 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid tert-butyl-ethyl-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-tert-Butylethylamine | HCID 521156 | — |
| Reactant | 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid | HCID 90203809 | — |
| Product | 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid tert-butyl-ethyl-amide | HCID 90204590 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 23b, using 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42c) and N-ethyl-2-methylpropan-2-amine (CAN 4432-77-3) as starting materials and isolated (9 mg, 4.5%) as colorless oil; MS (ESI, m/z): 317.6 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409866B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-dcaeecffa1a640fcb497b8390c076db5 |
| Source note | uspto-grants-2016_08 |