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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1480175Generated: October 30, 2026

(2S)-1,1,1-Trifluoropropan-2-ol → HCID 90203925, compound

https://huagongshe.com/reaction/1480175

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S)-1,1,1-Trifluoropropan-2-olHCID 6999971—
ReactantHCID 90203880HCID 90203880—
ProductHCID 90203925HCID 90203925—

Reaction Steps

The title compound was synthesized in analogy to Example 108b, using 1-(4-Chloro-pyridin-3-yl)-cyclobutanol (Example 108a) and (S)-1,1,1-trifluoropropan-2-ol (CAN 3539-97-7) as starting materials and isolated (3.22 g, 57%) as yellow oil; MS (ESI, m/z): 262.3 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09409866B2
Source datasetuspto-grants-2016_08
ORD IDord-2cf5d725d0a94656b124946c41e980c3
Source noteuspto-grants-2016_08