HRID1480184

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID45158907

4,4-Difluoro-D-prolinamide--hydrogen chloride (1/1)

C5H9ClF2N2O

HCID90203674

未命名化合物

PRODUCTS

生成物

结构：NC(=O)[C@@H]1CC(F)(F)CN1C(=O)c1cc(OCC(F)(F)F)c(C2CC2)cn1

HCID76284484

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized in analogy to Example 112e, using 5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (Example 48c) and (R)-4,4-difluoropyrrolidine-2-carboxamide hydrochloride (CAN 719267-96-6) as starting materials and isolated (33 mg, 44%); MS (ESI, m/z): 394.5 (M+H+).

WORKUP

后处理

customisolated (33 mg, 44%)