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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1480193Generated: October 30, 2026

(2S)-1,1,1-Trifluoropropan-2-ol → HCID 90214921, compound

https://huagongshe.com/reaction/1480193

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S)-1,1,1-Trifluoropropan-2-olHCID 6999971—
ReactantHCID 90203579HCID 90203579—
ProductHCID 90214921HCID 90214921—

Reaction Steps

The title compound was synthesized in analogy to Example 123c, using 4-chloro-5-(1-hydroxycyclobutyl)pyridine-2-carbonitrile (example 126b) and (S)-1,1,1-Trifluoro-propan-2-ol (CAN 3539-97-7) as starting materials and isolated (1.2 g, 92%); MS (ESI, m/z): 287.5 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09409866B2
Source datasetuspto-grants-2016_08
ORD IDord-70de42e2bd604a19affe6cbab30a2acb
Source noteuspto-grants-2016_08