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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1480222Generated: November 2, 2026

5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid → HCID 90203258, compound

https://huagongshe.com/reaction/1480222

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acidHCID 90203674—
ReactantHCID 90204489HCID 90204489—
ProductHCID 90203258HCID 90203258—

Reaction Steps

The title compound was synthesized in analogy to Example 112e, using 5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (example 48c) and ethyl 2-amino-2-(5-methyl-1,2,4-oxadiazol-3-yl)propanoate (example 147a) as starting materials and isolated (508 mg, 86%); MS (ESI, m/z): 443.5 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09409866B2
Source datasetuspto-grants-2016_08
ORD IDord-2447b1653e7246a68d8fa6b2b5152614
Source noteuspto-grants-2016_08