HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 90204175, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 3,3-Difluoroazetidine | HCID 2758248 | — |
| Reactant | HCID 90203702 | HCID 90203702 | — |
| Product | HCID 90204175 | HCID 90204175 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 112e, using 2-[[5-cyclopropyl-4-(2,2,2-trifluoroethoxy)pyridine-2-carbonyl]amino]-2-(5-methyl-1,2,4-oxadiazol-3-yl)propanoic acid (Example 147c) and 3,3-Difluoro-azetidine; hydrochloride (CAN 288315-03-7) as starting materials and isolated (18 mg, 24%); MS (ESI, m/z): 490.5 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409866B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-42b25c61105647e190d24d2be8053761 |
| Source note | uspto-grants-2016_08 |