Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1480227Generated: November 1, 2026

2-Amino-3-cyclopropyl-2-methyl-propionitrile → HCID 90203688, compound

https://huagongshe.com/reaction/1480227

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-3-cyclopropyl-2-methyl-propionitrileHCID 84716049—
Reactant5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acidHCID 90203674—
ProductHCID 90203688HCID 90203688—

Reaction Steps

The title compound was synthesized in analogy to Example 112e, using 5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (Example 48c) and 2-Amino-3-cyclopropyl-2-methyl-propionitrile (example 66a) as starting materials and isolated (376 mg, 67%); MS (ESI, m/z): 368.6 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09409866B2
Source datasetuspto-grants-2016_08
ORD IDord-57f5ff5f666441cd8f48ea958d0e2fe9
Source noteuspto-grants-2016_08