HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 90204489, compound → HCID 90214978, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 90204489 | HCID 90204489 | — |
| Reactant | 5-(3-fluorooxetan-3-yl)-4-[(1S)-2,2,2-trifluoro-1-methyl-ethoxy]pyridine-2-carboxylic acid | HCID 90214950 | — |
| Product | HCID 90214978 | HCID 90214978 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 112e, using 5-(3-fluorooxetan-3-yl)-4-[(1S)-2,2,2-trifluoro-1-methyl-ethoxy]pyridine-2-carboxylic acid (example 142b) and ethyl 2-amino-2-(5-methyl-1,2,4-oxadiazol-3-yl)propanoate (example 147a) as starting materials and isolated (283 mg, purity: 86%, 57%); MS (ESI, m/z): 491.5 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409866B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-879527ae04874eb69fa13e49b2d9fa66 |
| Source note | uspto-grants-2016_08 |