Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1480258Generated: November 1, 2026

5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid → HCID 90203565, compound

https://huagongshe.com/reaction/1480258

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acidHCID 90203674—
ReactantHCID 90204397HCID 90204397—
ProductHCID 90203565HCID 90203565—

Reaction Steps

The title compound was synthesized in analogy to Example 112e, using 5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (Example 48c) and tert-butyl 2-amino-3-cyclopropyl-2-methyl-propanoate (example 186b) as starting materials and isolated (105 mg, 31%); MS (ESI, m/z): 443.6 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09409866B2
Source datasetuspto-grants-2016_08
ORD IDord-325246533a654870a3fdd29d7648372f
Source noteuspto-grants-2016_08