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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1480264Generated: October 31, 2026

3-Amino-3-cyclopropylpropanamide hydrochloride → HCID 76281193, compound

https://huagongshe.com/reaction/1480264

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-3-cyclopropylpropanamide hydrochlorideHCID 54595151—
Reactant5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acidHCID 90203674—
ProductHCID 76281193HCID 76281193—

Reaction Steps

The title compound was synthesized in analogy to Example 112e, using 5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (Example 48c) and 3-amino-3-cyclopropylpropanamide hydrochloride (CAN 1354953-76-6) as starting materials and isolated (50 mg, 35%); MS (ESI, m/z): 372.5 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09409866B2
Source datasetuspto-grants-2016_08
ORD IDord-fec184b3e47740a5ad65ec4d8df66250
Source noteuspto-grants-2016_08