HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalate → HCID 90204920, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalate | HCID 71081 | — |
| Reactant | 6-Oxa-1-azaspiro(3.3)heptane | HCID 54759146 | — |
| Reactant | 2-[[5-cyclopropyl-4-[(1S)-2,2,2-trifluoro-1-methyl-ethoxy]pyridine-2-carbonyl]amino]-3,3-dimethyl-butanoic acid | HCID 90203539 | — |
| Product | HCID 90204920 | HCID 90204920 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 112e, using 2-[[5-cyclopropyl-4-[(1S)-2,2,2-trifluoro-1-methyl-ethoxy]pyridine-2-carbonyl]amino]-3,3-dimethyl-butanoic acid (Example 199b) and 6-Oxa-1-azaspiro[3.3]heptane, ethanedioate (1:2) (CAN 1380571-72-1) as starting materials and isolated (23 mg, 38%); MS (ESI, m/z): 470.6 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409866B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-980db6929550421e8004a936d05c1674 |
| Source note | uspto-grants-2016_08 |