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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1480304Generated: November 1, 2026

5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid → HCID 76280925, compound

https://huagongshe.com/reaction/1480304

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acidHCID 90203674—
ReactantHCID 90204007HCID 90204007—
ProductHCID 76280925HCID 76280925—

Reaction Steps

The title compound was synthesized in analogy to Example 112e, using 5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (example 48c) and (5-methyl-1,3,4-oxadiazol-2-yl)-(3-methyloxetan-3-yl)methanamine (example 245b) as starting materials and isolated (25 mg, 35%); MS (ESI, m/z): 427.7 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09409866B2
Source datasetuspto-grants-2016_08
ORD IDord-ecf20741f8fd4129bc5df5828bf7acc0
Source noteuspto-grants-2016_08