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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1480322Generated: October 31, 2026

5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid → HCID 90204763, compound

https://huagongshe.com/reaction/1480322

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acidHCID 90203674—
ReactantHCID 90204553HCID 90204553—
ProductHCID 90204763HCID 90204763—

Reaction Steps

The title compound was synthesized in analogy to Example 112e, using 5-Cyclopropyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (example 48c) and 2-amino-2-(3-methyloxetan-3-yl)acetonitrile (example 251b) as starting materials and isolated (105 mg, 85%); MS (ESI, m/z): 370.3 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09409866B2
Source datasetuspto-grants-2016_08
ORD IDord-d9a163fafba24bc0a13d56941b502231
Source noteuspto-grants-2016_08