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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1480375Generated: November 1, 2026

2-Oxo-5-methyl-4-oxazoline-4-carboxylic acid → 3,5-Dichlorobenzyl 4-(2-(N,5-dimethyl-2-oxo-2,3-dihydrooxazole-4-carboxamido)ethyl)piperidine-1-carboxylate

https://huagongshe.com/reaction/1480375

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Oxo-5-methyl-4-oxazoline-4-carboxylic acidHCID 53709208—
ReactantHCID 86722625HCID 86722625—
Product3,5-Dichlorobenzyl 4-(2-(N,5-dimethyl-2-oxo-2,3-dihydrooxazole-4-carboxamido)ethyl)piperidine-1-carboxylateHCID 86722631—

Reaction Steps

The title compound was prepared from 3,5-dichlorobenzyl 4-(2-methylamino)ethyl)piperidine-1-carboxylate (Example 1, step 3) and 5-methyl-2-oxo-2,3-dihydrooxazole-4-carboxylic acid analogously to Example 6;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09409895B2
Source datasetuspto-grants-2016_08
ORD IDord-4b0067e3e7eb4b6ca9ac9bceb7130567
Source noteuspto-grants-2016_08