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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1480406Generated: November 1, 2026

tert-Butyl 4-(2-aminoethyl)piperidine-1-carboxylate → Tert-butyl 4-(2-(2-oxo-2,3-dihydrooxazole-5-carboxamido)ethyl)piperidine-1-carboxylate

https://huagongshe.com/reaction/1480406

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl 4-(2-aminoethyl)piperidine-1-carboxylateHCID 1514258—
Reactant2-Hydroxy-1,3-oxazole-5-carboxylic acidHCID 53981423—
ProductTert-butyl 4-(2-(2-oxo-2,3-dihydrooxazole-5-carboxamido)ethyl)piperidine-1-carboxylateHCID 86722643—

Reaction Steps

The title compound was prepared from 2-oxo-2,3-dihydrooxazole-5-carboxylic acid (step 1) and tert-butyl 4-(2-aminoethyl)piperidine-1-carboxylate analogously to Example 20 step 4;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09409895B2
Source datasetuspto-grants-2016_08
ORD IDord-db1e01be21b14b8698b4e99d5cff77aa
Source noteuspto-grants-2016_08