HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Hydroxy-1,3-oxazole-5-carboxylic acid → 3,5-Dichlorobenzyl 4-(2-(2-oxo-2,3-dihydrooxazole-5-carboxamido)ethyl)piperazine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Hydroxy-1,3-oxazole-5-carboxylic acid | HCID 53981423 | — |
| Reactant | 3,5-Dichlorobenzyl 4-(2-aminoethyl)piperazine-1-carboxylate | HCID 86722652 | — |
| Product | 3,5-Dichlorobenzyl 4-(2-(2-oxo-2,3-dihydrooxazole-5-carboxamido)ethyl)piperazine-1-carboxylate | HCID 86722651 | — |
Reaction Steps
The title compound was prepared from 2-oxo-2,3-dihydrooxazole-5-carboxylic acid (Example 21 step 1) and 3,5-dichlorobenzyl 4-(2-aminoethyl)piperazine-1-carboxylate (step 2) analogously to Example 15 step 3;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409895B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-a397f7b7e8ea4f9d921a7640c8720826 |
| Source note | uspto-grants-2016_08 |