HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178483276, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | HCID 178483293 | HCID 178483293 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 178483276 | HCID 178483276 | — |
Reaction Steps
To tert-butyl 4-(2-(N-methyl-1H-1,2,3-triazole-4-carboxamido)ethyl)piperidine-1-carboxylate (step 2) (190 mg, 0.563 mmol) in EtOAc (5 ml) was added 4N HCl in dioxane (5 ml, 20.00 mmol). The mixture was stirred for 30 mins and concentrated under reduced pressure to give crude N-methyl-N-(2-(piperidin-4-yl)ethyl)-1H-1,2,3-triazole-4-carboxamide as a gum. This was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409895B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-8058b4b6dee845188f043dfeccfb93b0 |
| Source note | uspto-grants-2016_08 |