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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1480436Generated: October 31, 2026

Hydrochloric Acid → HCID 178483276, compound

https://huagongshe.com/reaction/1480436

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1,4-DioxaneHCID 31275—
ReactantHCID 178483293HCID 178483293—
SolventEthyl AcetateHCID 8857—
ProductHCID 178483276HCID 178483276—

Reaction Steps

To tert-butyl 4-(2-(N-methyl-1H-1,2,3-triazole-4-carboxamido)ethyl)piperidine-1-carboxylate (step 2) (190 mg, 0.563 mmol) in EtOAc (5 ml) was added 4N HCl in dioxane (5 ml, 20.00 mmol). The mixture was stirred for 30 mins and concentrated under reduced pressure to give crude N-methyl-N-(2-(piperidin-4-yl)ethyl)-1H-1,2,3-triazole-4-carboxamide as a gum. This was used in the next step without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09409895B2
Source datasetuspto-grants-2016_08
ORD IDord-8058b4b6dee845188f043dfeccfb93b0
Source noteuspto-grants-2016_08