HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86722713, compound → HCID 178452124, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86722713 | HCID 86722713 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178452124 | HCID 178452124 | — |
Reaction Steps
Tert-butyl 4-(6-(1-benzyl-1H-1,2,3-triazol-4-yl)hexanamido)piperidine-1-carboxylate (187 mg, 0.410 mmol) was dissolved in ethanol (10 ml) to give a yellow solution. The solution was then submitted to continuous flow hydrogenation using H-cube hydrogenation apparatus, at 70° C. and 30 bar hydrogen pressure for 2 hours. The resultant solution was concentrated under reduced pressure to yield the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409895B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-e1977b7cd9164f47a8b9bfb598945e3e |
| Source note | uspto-grants-2016_08 |