1,4-Butane sultone → 4-(5-Chloro-2,3,3-trimethyl-3H-pyrrolo[2,3-b]pyridin-7-ium-7-yl)butane-1-sulfonate

HRID 1480513Notes

Reaction equation

HRID 1480513 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:17]([CH3:19])([CH3:18])[C:16]([CH3:20])=[N:15][C:5]2=[N+:6]([CH2:8][CH2:9][CH2:10]S([O-])(=O)=O)[CH:7]=1.C1C[O:27][S:24](=[O:26])(=[O:25])[CH2:23]C1>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:17]([CH3:18])([CH3:19])[C:16]([CH3:20])=[N:15][C:5]2=[N+:6]([CH2:8][CH2:9][CH2:10][CH2:23][S:24]([O-:27])(=[O:26])=[O:25])[CH:7]=1

Participants

3

Reactant 2

HCID 154111,4-Butane sultoneHCID 866994663-(5-Chloro-2,3,3-trimethyl-3H-pyrrolo[2,3-b]pyridin-7-ium-7-yl)propane-1-sulfonate

Product 1

HCID 898463294-(5-Chloro-2,3,3-trimethyl-3H-pyrrolo[2,3-b]pyridin-7-ium-7-yl)butane-1-sulfonate

Procedure

Compound 26 is prepared analogously to compound 5 (Example 5), except that 1,4-butanesultone is used as a starting material.

Sources & evidence

ORD record
ord-3878c5e07bbe4f49ae84dacd349a9a88
Source dataset
uspto-grants-2016_08
Patent number
US09408924B2

Reaction notes

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