Dichloromethane → N-[2-(3-{6-[2-(2-fluoro-4-trifluoromethyl-phenyl)-ethylamino]-2-methoxy-pyrimidin-4-yl}-phenyl)-ethyl]-acetamide
Reaction equation
[CH3:32][CH2:33][N:34]([CH2:35][CH3:36])[CH2:37][CH3:38].[CH3:39][C:40]([Cl:41])=[O:42].[Cl:43][CH2:44][Cl:45].[NH2:1][CH2:2][CH2:3][c:4]1[cH:5][c:6](-[c:10]2[cH:11][c:12]([NH:18][CH2:19][CH2:20][c:21]3[c:22]([F:31])[cH:23][c:24]([C:27]([F:28])([F:29])[F:30])[cH:25][cH:26]3)[n:13][c:14]([O:16][CH3:17])[n:15]2)[cH:7][cH:8][cH:9]1>>[NH:1]([CH2:2][CH2:3][c:4]1[cH:5][c:6](-[c:10]2[cH:11][c:12]([NH:18][CH2:19][CH2:20][c:21]3[c:22]([F:31])[cH:23][c:24]([C:27]([F:28])([F:29])[F:30])[cH:25][cH:26]3)[n:13][c:14]([O:16][CH3:17])[n:15]2)[cH:7][cH:8][cH:9]1)[C:40]([CH3:39])=[O:42]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-3cae2a3fd6cf4ed0840950fa3fc550b1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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