[5-(Trifluoromethyl)pyridin-3-yl]boronic acid → HCID 86718565, Verbindung

HRID 1480610Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1480610
Br[C:2]1[C:11]2[O:10]C[N:8]([C:12]([CH3:15])([CH3:14])[CH3:13])[CH2:7][C:6]=2[CH:5]=[C:4]([C:16]([CH3:19])([CH3:18])[CH3:17])[CH:3]=1.[F:20][C:21]([F:32])([F:31])[C:22]1[CH:23]=[N:24][CH:25]=[C:26](B(O)O)[CH:27]=1>>[C:16]([C:4]1[CH:3]=[C:2]([C:26]2[CH:25]=[N:24][CH:23]=[C:22]([C:21]([F:32])([F:31])[F:20])[CH:27]=2)[C:11]([OH:10])=[C:6]([CH2:7][NH:8][C:12]([CH3:13])([CH3:14])[CH3:15])[CH:5]=1)([CH3:17])([CH3:18])[CH3:19]

Komponenten

3

Edukt 2

HCID 45158900[5-(Trifluoromethyl)pyridin-3-yl]boronic acid2×HCID 867185598-bromo-3,6-di-tert-butyl-3,4-dihydro-2H-benzo[e][1,3]oxazine2×

Produkt 1

HCID 86718565HCID 86718565, Verbindung

Versuchsvorschrift

The title compound was prepared as a white solid using the procedure described in Example 1 from 8-bromo-3,6-di-tert-butyl-3,4-dihydro-2H-benzo[e][1,3]oxazine (Intermediate 1) and 3-(trifluoromethyl)pyridine-5-boronic acid [Intermediate 2].

Quellen und Nachweise

ORD-Eintrag
ord-9d22387ac6d14a1c80e8e8a5ba7b162a
Quelldatensatz
uspto-grants-2016_08
Patentnummer
US09409893B2

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