HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloropyridine-5-boronic acid → 4-(tert-Butyl)-2-((tert-butylamino)methyl)-6-(6-chloropyridin-3-yl)phenol hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloropyridine-5-boronic acid | HCID 3845034 | — |
| Reactant | 8-bromo-3,6-di-tert-butyl-3,4-dihydro-2H-benzo[e][1,3]oxazine | HCID 86718559 | — |
| Product | 4-(tert-Butyl)-2-((tert-butylamino)methyl)-6-(6-chloropyridin-3-yl)phenol hydrochloride | HCID 86718568 | — |
Reaction Steps
The title compound was prepared as a white solid using the procedure described in Example 1 from 8-bromo-3,6-di-tert-butyl-3,4-dihydro-2H-benzo[e][1,3]oxazine (Intermediate 1) and 2-chloropyridine-5-boronic acid [purchased from Frontier Scientific].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409893B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-477055a73dff4b5c894c8c3234ce4546 |
| Source note | uspto-grants-2016_08 |