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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1480856Generated: November 2, 2026

(3-Methyloxolan-3-yl)methanamine → N-((3-methyltetrahydrofuran-3-yl)methyl)-2-(methylthio)pyrido[3,4-d]pyrimidin-8-amine

https://huagongshe.com/reaction/1480856

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-Methyloxolan-3-yl)methanamineHCID 54593129—
Reactant8-Chloro-2-(methylthio)pyrido[3,4-d]pyrimidineHCID 89996025—
ProductN-((3-methyltetrahydrofuran-3-yl)methyl)-2-(methylthio)pyrido[3,4-d]pyrimidin-8-amineHCID 89996205—

Reaction Steps

The title compound was prepared according to the method described for Preparation 175 using of 8-chloro-2-(methylthio)pyrido[3,4-d]pyrimidine (Preparation 33) and (3-methyltetrahydrofuran-3-yl)methanamine at 130° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09409907B2
Source datasetuspto-grants-2016_08
ORD IDord-695809c229864192b3373cbec3ba42cf
Source noteuspto-grants-2016_08