HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Morpholinopiperidine → 4-[1-(3-Methoxy-4-nitrophenyl)piperidin-4-yl]morpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Morpholinopiperidine | HCID 795724 | — |
| Reactant | 5-Fluoro-2-nitroanisole | HCID 2779250 | — |
| Product | 4-[1-(3-Methoxy-4-nitrophenyl)piperidin-4-yl]morpholine | HCID 57416154 | — |
Reaction Steps
The title compound was prepared according to the method described for Preparation 78 using 4-fluoro-2-methoxy-1-nitrobenzene and 4-(piperidin-4-yl)morpholine. The residue was purified using silica gel column chromatography eluting with 80-100% DCM in cyclohexanes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409907B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-684b0b21b168427d8842dd17a318efb4 |
| Source note | uspto-grants-2016_08 |