HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylpiperazine → 1-(3-Methoxy-4-nitrophenyl)-4-methylpiperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 5-Fluoro-2-nitroanisole | HCID 2779250 | — |
| Product | 1-(3-Methoxy-4-nitrophenyl)-4-methylpiperazine | HCID 56777243 | — |
Reaction Steps
The title compound was prepared according to the method described for Preparations 78 and 79 using 4-fluoro-2-methoxy-1-nitrobenzene and 1-methylpiperazine. The residue was purified by silica gel column chromatography eluting with 0-20% MeOH in EtOAc.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409907B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-c4e51632a78b430a812bec9d65796c9b |
| Source note | uspto-grants-2016_08 |