HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Methylsulfonyl)piperazine → 1-(3-Methoxy-4-nitro-phenyl)-4-methylsulfonyl-piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Methylsulfonyl)piperazine | HCID 709161 | — |
| Reactant | 5-Fluoro-2-nitroanisole | HCID 2779250 | — |
| Product | 1-(3-Methoxy-4-nitro-phenyl)-4-methylsulfonyl-piperazine | HCID 59860255 | — |
Reaction Steps
The title compound was prepared according to the method described for Preparation 78 using 4-fluoro-2-methoxy-1-nitrobenzene and 1-(methylsulfonyl)piperazine for 96 hours. The residue was purified by silica gel column chromatography eluting with 50-100% DCM in cyclohexanes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409907B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-1d5cb459ac8f464a90470f2296702634 |
| Source note | uspto-grants-2016_08 |