Sodium Acetate → HCID 117819008, compound

Participants

Reaction Steps

To a suspension of furo[2,3-b]pyridine-3-carboxylic acid methyl ester (48 mmol) in 180 mL MeOH was added NaOAc (97 mmol). The flask was evacuated and filled three times with argon, 20% wet Pd(OH)2 on carbon (1000 mg) was added and the reaction was stirred for 20 h under a hydrogen atmosphere. It was then filtered over a 2 cm pad of celite and was washed with EtOH (50 mL) and EtOAc (50 mL). The filtrate was concentrated in vacuo to afford the desired compound as colorless oil.

Provenance & Evidence