HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → 2-(2-Cyclopropylpyrimidin-5-yl)-2-morpholinoethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | 2-Cyclopropylpyrimidine-5-carbaldehyde | HCID 24903623 | — |
| Reactant | 2-(4,4-Difluoropiperidin-1-yl)-2-(4-(trifluoromethyl)phenyl)-ethanamine | HCID 89704691 | — |
| Product | 2-(2-Cyclopropylpyrimidin-5-yl)-2-morpholinoethanamine | HCID 89704707 | — |
Reaction Steps
This compound was prepared using a method analogous to that of 2-(4,4-difluoropiperidin-1-yl)-2-(4-(trifluoromethyl)phenyl)-ethanamine (A.2.18), 2-cyclopropylpyrimidine-5-carbaldehyde replacing 4-(trifluoromethyl)benzaldehyde and morpholine replacing 4,4-difluoropiperidine HCl.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409917B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-2a8d99e46ef64b2786a02d1b470293a6 |
| Source note | uspto-grants-2016_08 |