Acetone hexane → HCID 90011170, compound

Participants

Reaction Steps

Step-2: 1-(5-Bromopyridin-2-yl)-N′-(propan-2-ylidene)-5-(trifluoromethyl)-1H-pyrazole-3-carbohydrazide: A solution of step-1 intermediate (1.0 g, 2.86 mmol) in acetone: hexane (1:1, 12 mL) was stirred at 70° C. for 3 h. The reaction was then cooled to room temperature and the solvent was evaporated under vacuum to afford 800 mg (72%) of the title compound as white solid. ESI-MS (m/z) 390, 392 [(MH)+, Br79,81].

Provenance & Evidence