Methanol → (1-Methoxyethyl)benzene

Temperature

90 °C

Into a pressure vessel methanol (84 μL, 1 mmol, 1 eq) was added and diluted with ethylbenzene (1.225 mL, 10 mmol, 10 eq). To this stirring solution was added 1 mol % of a stock solution of {[Cl2NN]Cu}2(benzene) from the catalyst stock solution described in Example 4 (200 μL=0.01 mmol). After adding of tert-butyl peroxide (220 μL, 1.2 mmol), the pressure vessel was sealed and heated to 90° C. for 24 hr. The catalyst was separated by exposing the mixture to air and filtering through Celite®. After removing ethylbenzene under vacuum, the residue was analyzed by GC/MS and 1H NMR to determine the yield and consumption of starting materials. 1H NMR Yield: 35%.

1. customthe pressure vessel was sealed
2. customThe catalyst was separated
3. filtrationfiltering through Celite®
4. customAfter removing ethylbenzene under vacuum
5. customyield
6. customconsumption of starting materials

ORD record

ord-ef33535f270348ecb34c7c17495ca65c

Source dataset

uspto-grants-2016_08

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US09416080B2