HCID 90079356, compound → HCID 66212377, compound

Participants

Reaction Steps

1.2 5-(4-Bromo-benzoyl)-hexahydro-pyrrolo[3,4-c]pyrrole-2-carboxylic acid tert-butyl ester (1.1 g; 2.78 mmol) is dissolved in 15 ml of HCl/Isopropanol (5-6N) and then stirred at RT for 2 hrs. The reaction mixture is reduced to dryness under vacuo to yield 0.90 g (97.5%) (4-bromo-phenyl)-(hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-methanone 2.

Provenance & Evidence