HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 136341389, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2,2,2-Trifluoroethylamine hydrochloride | HCID 9772 | — |
| Reactant | HCID 178479679 | HCID 178479679 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 136341389 | HCID 136341389 | — |
Reaction Steps
To a solution of 2,2,2-Trifluoroethylamine hydrochloride (Sigma-Aldrich) (15.2 g, 113.2 mmol) in acetonitrile (36 mL) was added 3-pyrazole carboxaldehyde hydrochloride (which could be prepared as described in Traydakov, et. al., Synthetic Communications, 2011, 41, 2430-2434) (10 g, 75.75 mmol) followed by triethylamine (31.5 ml, 226.4 mmol) at 0° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09416124B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-c5792f886f1e45c79d3b68f7db9884cf |
| Source note | uspto-grants-2016_08 |