Potassium Carbonate → HCID 71601826, compound

Participants

Reaction Steps

Compound 24b (200 mg, 0.63 mmol) was dissolved in methanol (8 mL). Potassium carbonate (175 mg, 1.27 mmol) was added. Under the protection of argon, the mixture was allowed to react at room temperature for 5 hrs. The reaction was monitored by TLC (petroleum ether/ethyl acetate=5/1). After the reaction completed, the mixture was diluted with water, and extracted with ethyl acetate. The organic phase was combined, washed with saturated sodium chloride solution, dried over anhydrous sodium sulfate. Column chromatography (petroleum ether/ethyl acetate=5/1) afforded 120 mg of white solid (compound 24c), yield 70%.

Provenance & Evidence