Tetrahydrofuran → tert-butyl N-[1-hydroxy-3-[4-(trifluoromethyl)phenyl]butan-2-yl]carbamate
Reaction equation
[C:1]([Si:2]([CH3:3])([CH3:4])[O:6][CH2:7][CH:8]([CH:9]([CH3:10])[c:11]1[cH:12][cH:13][c:14]([C:17]([F:18])([F:19])[F:20])[cH:15][cH:16]1)[NH:21][C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])([CH3:5])([CH3:29])[CH3:30].[CH2:49]1[O:50][CH2:51][CH2:52][CH2:53]1.[CH3:32][CH2:33][CH2:34][CH2:35][N+:36]([CH2:37][CH2:38][CH2:39][CH3:40])([CH2:41][CH2:42][CH2:43][CH3:44])[CH2:45][CH2:46][CH2:47][CH3:48].[F-:31]>>[OH:6][CH2:7][CH:8]([CH:9]([CH3:10])[c:11]1[cH:12][cH:13][c:14]([C:17]([F:18])([F:19])[F:20])[cH:15][cH:16]1)[NH:21][C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28]Participants
5
Sources & evidence
- ORD record
- ord-c6768c61cf1e48b7a38b91d3235c57f3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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