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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 14838Generated: October 29, 2026

3-Aminopyridine → [3-(2-Chloro-pyrimidin-4-yl)-benzyl]-pyridin-3-yl-amine

https://huagongshe.com/reaction/14838

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-AminopyridineHCID 10009—
Reactant3-(2-Chloro-pyrimidin-4-yl)-benzaldehydeHCID 24901965—
Product[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-pyridin-3-yl-amineHCID 86603282—

Reaction Steps

Intermediate 1 was coupled with 3-aminopyridine following procedure B. LC-MS showed the product had the expected M+H+ of 297.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07732444B2
Source datasetuspto-grants-2010_06
ORD IDord-1a26662e7b0f40a1998da26103818dae
Source noteuspto-grants-2010_06