4-(3-(Methylsulfonyl)phenyl)piperidine → 4-(3-Methanesulfonyl-phenyl)-1-butyl-piperidine

HRID 1483897Notes

Reaction equation

HRID 1483897 reaction equation
[CH3:1][S:2]([C:5]1[CH:6]=[C:7]([CH:11]2[CH2:16][CH2:15][NH:14][CH2:13][CH2:12]2)[CH:8]=[CH:9][CH:10]=1)(=[O:4])=[O:3]>C(Cl)CCC>[CH3:1][S:2]([C:5]1[CH:6]=[C:7]([CH:11]2[CH2:16][CH2:15][N:14]([CH2:6][CH2:5][CH2:10][CH3:9])[CH2:13][CH2:12]2)[CH:8]=[CH:9][CH:10]=1)(=[O:4])=[O:3]

Participants

3

Reactant 1

HCID 129889574-(3-(Methylsulfonyl)phenyl)piperidine

Product 1

HCID 99007934-(3-Methanesulfonyl-phenyl)-1-butyl-piperidine

Reagents, catalysts & solvents 1

HCID 8005Butyl ChlorideSolvent

Procedure

Beginning with 4-(3-methanesulfonyl-phenyl)-piperidine and n-BuCl. MS m/z (rel. intensity, 70 eV) 295 (M+, 3), 252 (bp), 130 (5), 115 (3), 70 (8).

Sources & evidence

ORD record
ord-8ee88743835649f68d241117ed737a18
Source dataset
uspto-grants-2016_08
Patent number
USRE046117E1

Reaction notes

Loading…