HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phentermine → beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, 1-sulfamate, mixt. with alpha,alpha-dimethylbenzeneethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phentermine | HCID 4771 | — |
| Reactant | Phentermine Hydrochloride | HCID 70969 | — |
| Reactant | Topiramate | HCID 5284627 | — |
| Product | beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, 1-sulfamate, mixt. with alpha,alpha-dimethylbenzeneethanamine | HCID 9848354 | — |
Reaction Steps
The sustained-release pellet of topiramate as prepared in Example 12 and the phentermine pellet as prepared according to Formulation 19 in Example 11 were homogeneously mixed in certain weight ratio via content calculation, and then filled into capsules so that each capsule contained 23 mg of topiramate and 4.67 mg of phentermine hydrochloride (corresponding to 3.75 mg of phentermine).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09421188B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-e62969ddd9174b64bf756ffa0df520e6 |
| Source note | uspto-grants-2016_08 |