HRID1484016

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID4771

Phentermine

C10H15N

HCID70969

Phentermine Hydrochloride

C10H16ClN

结构：CC1(C)O[C@@H]2[C@@H](CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@@H]23)O1

HCID5284627

Topiramate

C12H21NO8S

2 次

PRODUCTS

生成物

结构：CC(C)(N)Cc1ccccc1.CC1(C)O[C@@H]2[C@@H](CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@@H]23)O1

HCID9848354

未命名化合物

PROCEDURE

实验过程

The first batch of sustained-release pellet of topiramate as prepared in Example 6 and the phentermine pellet as prepared according to Formulation 19 in Example 11 were homogeneously mixed in certain weight ratio via content calculation, and then filled into capsules so that each capsule contained 23 mg of topiramate and 4.67 mg of phentermine hydrochloride (corresponding to 3.75 mg of phentermine).

WORKUP

后处理

additionwere homogeneously mixed in certain weight ratio via content calculation
additionfilled into capsules so that each capsule