Phentermine → beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, 1-sulfamate, mixt. with alpha,alpha-dimethylbenzeneethanamine

Participants

Reaction Steps

The first batch of sustained-release pellet of topiramate as prepared in Example 6 and the phentermine pellet as prepared according to Formulation 19 in Example 11 were homogeneously mixed in certain weight ratio via content calculation, and then filled into capsules so that each capsule contained 23 mg of topiramate and 4.67 mg of phentermine hydrochloride (corresponding to 3.75 mg of phentermine).

Provenance & Evidence