Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Spermidine | HCID 1102 | — |
| Reactant | Diethyl Maleate | HCID 5271566 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 86704359 | HCID 86704359 | — |
Reaction Steps
11.9 g (69 mmol) of diethyl maleate were added to a solution of 5 g (34.5 mmol) of spermidine in 5 ml of THF. The reaction mixture was stirred for 3 days at 60° C. After removing the solvent in vacuo, the product was obtained quantitatively as a yellow liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09421298B2 |
|---|
| Source dataset | uspto-grants-2016_08 |
|---|
| ORD ID | ord-a2973cd677db45f79d2518b4041bf0e7 |
|---|
| Source note | uspto-grants-2016_08 |
|---|
